SpotitEarly Knowledge Center

Nearly half of women screened have dense breast tissue, a common finding that can hide tumors on a mammogram and raise breast cancer risk. This article explains what breast density means, what causes it, and the screening options for dense breasts, from 3D mammography and MRI to emerging approaches like breath analysis, and introduces SpotitEarly's density-independent, breath-based screening.

A cancer test can flag a signal in minutes, but proving it helps patients takes years. This post explains what makes a good screening test, the validation and regulatory journey MCED tests follow, and how SpotitEarly is building the evidence behind its breath-based platform.

At the 2026 ASCO Annual Meeting, two of the largest multi-cancer early detection studies, PATHFINDER 2 and NHS-Galleri, reported their results. This article explains what they showed about detecting more cancers earlier and more safely, why one trial missed its primary endpoint, and what the findings mean for the future of cancer screening, including SpotitEarly's breath-based approach.

SpotitEarly plans to scale its technology to meet a growing global user base through the modular design of its LUCID platform. The approach combines automation, standardized VOC analysis, and patient-friendly sample collection. With adaptability for diverse environments and a focus on accessibility, SpotitEarly ensures consistent quality, efficiency, and reach in expanding cancer detection worldwide.

Obtaining and maintaining a CLIA certificate is required for laboratories that perform high complexity testing in the United States. This article explains what CLIA oversight involves and how SpotitEarly complies with these standards in its CLIA-registered lab. By meeting federal requirements for quality and accuracy, SpotitEarly ensures its Laboratory Developed Tests are performed in a safe, reliable, and clinically valid manner.

SpotitEarly advances cancer detection through its innovation pipeline, combining AI, automation, and VOC biomarker research. Enhanced data collection improves predictive accuracy and automation scales testing capacity. Together, these breakthroughs pave the way for a more accurate, accessible, and scalable future in early diagnosis.

The cancer detection industry is undergoing rapid transformation, driven by demand for earlier diagnosis, multi-cancer technologies, and AI integration. This article explores the trends shaping the field, from liquid biopsy development to accessibility challenges, and highlights how SpotitEarly addresses these gaps. With a bio-AI breath test platform detecting VOCs at early stages, SpotitEarly combines accuracy, accessibility, and transparency to help lead the cancer detectio

Cancer screening today is effective but limited, with most cancers lacking recommended tests. This article compares traditional methods like mammography and colonoscopy with new liquid biopsy approaches and introduces SpotitEarly’s breath-based test. By detecting volatile organic compounds (VOCs) through a bio-hybrid platform that combines canine olfaction with AI, SpotitEarly is advancing a non-invasive, accurate solution that complements current screening and expands early

SpotitEarly’s canine partners are at the heart of its early cancer detection platform. This article explores how the dogs are selected, trained, and cared for, and the science behind their extraordinary ability to detect cancer through scent. Learn about their daily work alongside handlers, the role they play in the hybrid canine-AI detection process, and how their skills contribute to making cancer screening accurate, non-invasive, and accessible.

Breath analysis is transforming the landscape of early cancer detection. By identifying volatile organic compounds (VOCs) in exhaled air, this non-invasive method can reveal disease indicators long before symptoms appear. This article explains the science behind breath-based biomarkers, how SpotitEarly integrates them with canine scent detection and AI, and why this approach offers accuracy, comfort, and scalability for global screening.

SpotitEarly welcomed Dr. J. Leonard “Len” Lichtenfeld as its first Chief Medical Officer to help accelerate early cancer detection. This article outlines his career leadership at the American Cancer Society, his vision for catching cancer earlier, and his priorities at SpotitEarly: advancing rigorous clinical research, building partnerships across healthcare, and securing the resources to scale access to innovative, non‑invasive screening worldwide.

SpotitEarly’s LUCID bio-hybrid platform unites the natural sensitivity of trained detection dogs with the precision of artificial intelligence. This article explores how the system captures and analyzes breath samples, integrates biological and technological strengths, and delivers accurate, scalable early cancer detection. Learn how LUCID is redefining what’s possible in non-invasive cancer screening.

The recent Rainbow clinical study, published in Nature Scientific Reports, showcases SpotitEarly’s extraordinary success. It shows SpotitEarly is able to detect cancer at early stages with sensitivity rates exceeding 90% for multiple cancers, including those with no standard screening options available today. This breakthrough positions SpotitEarly as a world leader in early disease detection technology.

Dogs possess an extraordinary sense of smell — capable of detecting volatile organic compounds linked to cancer at concentrations humans cannot perceive. This article will explain the biology of canine olfaction, the research behind scent-based cancer detection, and how SpotitEarly plans to train dogs as part of a hybrid platform with AI to make early, non-invasive cancer screening possible on a global scale.

SpotitEarly is developing a revolutionary approach to early cancer detection, combining the natural scent detection abilities of trained dogs with advanced AI analysis. This article introduces the company’s mission, technology, and vision for a future where non-invasive, accurate, and accessible screening is available worldwide. Learn how this hybrid platform aims to make early detection more effective and widely adopted.

At SpotitEarly, we are transforming the way cancer screening works, making it more accessible, accurate and user-friendly. Our innovative breath test is designed to detect cancer early, when survival rates are highest and treatment is most effective. But what will the full testing process look like for patients?

At the heart of SpotitEarly’s innovation are its partnerships with leading hospitals and research institutions worldwide. This post explains how these clinical collaborations validate the accuracy of its breath-based screening method, integrate with existing protocols, and enhance early cancer detection efforts. Learn how SpotitEarly’s platform works alongside—not against—current standards for better, non-invasive diagnostics.

SpotitEarly’s mission is to bring accurate, non-invasive cancer screening to people across the globe. In this post, we explore how our unique bio-AI hybrid approach, combining breath analysis with trained canine detection and artificial intelligence, is making early detection accessible, scalable, and effective. Learn how we’re fighting cancer by reaching more people, earlier, and saving lives.