SpotitEarly Knowledge Center

At the 2026 ASCO Annual Meeting, two of the largest multi-cancer early detection studies, PATHFINDER 2 and NHS-Galleri, reported their results. This article explains what they showed about detecting more cancers earlier and more safely, why one trial missed its primary endpoint, and what the findings mean for the future of cancer screening, including SpotitEarly's breath-based approach.

The global cancer diagnostics market is on track to reach $155 billion by 2030, with multi-cancer early detection (MCED) growing even faster. This article looks at the scale of the market, the gaps in current screening, the recent enactment of H.R. 842 into Medicare law, and the dynamics driving growth. It also positions SpotitEarly's breath-based pre-screening approach within an expanding category that is shifting healthcare from late treatment toward earlier detection.

SpotitEarly advances cancer detection through its innovation pipeline, combining AI, automation, and VOC biomarker research. Enhanced data collection improves predictive accuracy and automation scales testing capacity. Together, these breakthroughs pave the way for a more accurate, accessible, and scalable future in early diagnosis.

Cancer screening today is effective but limited, with most cancers lacking recommended tests. This article compares traditional methods like mammography and colonoscopy with new liquid biopsy approaches and introduces SpotitEarly’s breath-based test. By detecting volatile organic compounds (VOCs) through a bio-hybrid platform that combines canine olfaction with AI, SpotitEarly is advancing a non-invasive, accurate solution that complements current screening and expands early

SpotitEarly’s canine partners are at the heart of its early cancer detection platform. This article explores how the dogs are selected, trained, and cared for, and the science behind their extraordinary ability to detect cancer through scent. Learn about their daily work alongside handlers, the role they play in the hybrid canine-AI detection process, and how their skills contribute to making cancer screening accurate, non-invasive, and accessible.

Breath analysis is transforming the landscape of early cancer detection. By identifying volatile organic compounds (VOCs) in exhaled air, this non-invasive method can reveal disease indicators long before symptoms appear. This article explains the science behind breath-based biomarkers, how SpotitEarly integrates them with canine scent detection and AI, and why this approach offers accuracy, comfort, and scalability for global screening.

SpotitEarly welcomed Dr. J. Leonard “Len” Lichtenfeld as its first Chief Medical Officer to help accelerate early cancer detection. This article outlines his career leadership at the American Cancer Society, his vision for catching cancer earlier, and his priorities at SpotitEarly: advancing rigorous clinical research, building partnerships across healthcare, and securing the resources to scale access to innovative, non‑invasive screening worldwide.

SpotitEarly’s LUCID bio-hybrid platform unites the natural sensitivity of trained detection dogs with the precision of artificial intelligence. This article explores how the system captures and analyzes breath samples, integrates biological and technological strengths, and delivers accurate, scalable early cancer detection. Learn how LUCID is redefining what’s possible in non-invasive cancer screening.

The recent Rainbow clinical study, published in Nature Scientific Reports, showcases SpotitEarly’s extraordinary success. It shows SpotitEarly is able to detect cancer at early stages with sensitivity rates exceeding 90% for multiple cancers, including those with no standard screening options available today. This breakthrough positions SpotitEarly as a world leader in early disease detection technology.

SpotitEarly is developing a revolutionary approach to early cancer detection, combining the natural scent detection abilities of trained dogs with advanced AI analysis. This article introduces the company’s mission, technology, and vision for a future where non-invasive, accurate, and accessible screening is available worldwide. Learn how this hybrid platform aims to make early detection more effective and widely adopted.

At SpotitEarly, we are transforming the way cancer screening works, making it more accessible, accurate and user-friendly. Our innovative breath test is designed to detect cancer early, when survival rates are highest and treatment is most effective. But what will the full testing process look like for patients?